em. Prof. Dr. Karin Breunig
This site contents:
Patents (filed)
Breunig, K.D., Behrens, S.-E.: Method for the oral/mucosal vaccination by means of recombinant yeasts. International application No. PCT/DE 2009/001623 WO 2010/054649 (A2)
Breunig, K., Behrens, S.-E. Vaccination by means of recombinant yeast by producing a protective humoral response against defined antigens. International application No. PCT/DE2012/001205, WO 2013/107436 AI
Publications 2015
Mehlgarten C, Krijger JJ, Lemnian I, Gohr A, Kasper L, Diesing AK, Grosse I, Breunig KD (2015) Divergent Evolution of the Transcriptional Network Controlled by Snf1- Interacting Protein Sip4 in Budding Yeasts. PLoS One. 2015 Oct 6;10(10):e0139464. doi: 10.1371/journal.pone.0139464.
Glatt S, Zabel R, Vonkova I, Kumar A, Netz DJ, Pierik AJ, Rybin V, Lill R, Gavin AC, Balbach J, Breunig KD, Müller CW (2015) Structure of the Kti11/Kti13 heterodimer and its double role in modifications of tRNA and eukaryotic elongation factor 2. Structure 23(1):149-60. doi: 10.1016/j.str.2014.11.008
Publications 2014
Blüher D, Reinhardt-Tews A, Hey M, Lilie H, Golbik R, Breunig KD, Anders A. (2014) An ancient oxidoreductase making differential use of its cofactors. Biol Chem. 395:855-69. doi: 10.1515
Mates N, Kettner K, Heidenreich F, Pursche T, Migotti R, Kahlert G, Kuhlisch R, Breunig, KD, Schellenberger W, Dittmar G, Hoflack B, and Kriegel TM (2014) Proteomic and Functional Consequences of Hexokinase Deficiency in Glucose-Repressible Kluyveromyces lactis. Mol Cell Proteomics 2014 13: 860-875. doi:10.1074/mcp.M113.032714
Publications 2013
Simon C., Schaepe S., Breunig KD, Lilie H. (2013) Production of polyomavirus-like particles in a Klgal80 knockout strain of the yeast Kluyveromyces lactis. Prep Biochem Biotechnol 43:217-235.
Publications 2012
Arnold M, Durairaj V, Mundt E, Schulze K, Breunig KD, Behrens SE (2012) Protective vaccination against Infectious Bursal Disease Virus with whole recombinant Kluyveromyces lactis yeast expressing the viral VP2 subunit. PLoS One 7(9):e42870
Krijger J-J, Baumann J, Wagner M, Schulze K, Reinsch C, Klose T, Onuma OF, Simon C, Behrens SE, Breunig, KD (2012) A novel, lactase-based selection and strain improvement strategy for recombinant protein expression in Kluyveromyces lactis. Microb. Cell Fact. 11: 112ff
Publications 2011
Rigamonte,TA.; Silveira,WB.; Fietto,.G.; Castro,IM.; Breunig,KD.; Passos,FM.(2011) Restricted sugar uptake by sugar-induced internalization of the yeast lactose/galactose permease Lac12. FEMS Yeast Res. 11: 243-251.
Anders, A and Breunig, KD (2011) Evolutionary aspects of a genetic network: Studying the lactose/galactose regulon of Kluyveromyces lactis. Methods Mol.Biol. 234: 259-277.
Publications 2010
Mehlgarten, C, Jablonowski, D, Wrackmeyer, U, Tschitschmann, S, Sondermann, D, Jager, G, Gong, Z, Bystrom, AS., Schaffrath, R, and Breunig, KD (2010) Elongator function in tRNA wobble uridine modification is conserved between yeast and plants. Mol Microbiol. 76, 1082-1094
Publications 2009
Mehlgarten, Constance; Jablonowski, Daniel; Breunig, Karin D. ; Stark, Michaelj R.; Schaffrath, Raffael Elongator function depends on antagonistic regulation by casein kinase Hrr25 and protein phosphatase Sit4 *
In: Molecular microbiology . - Oxford : Blackwell, ISSN 0950-382x, Bd. 73.2009, 5, S. 869-881, insges. 13 S.
Publications 2008
Rodicio, Rosaura; López, Maria Luz; Cuadrado, Sara; Cid, Alejandra F.; Redruello, Begoña; Moreno, Fernando; Heinisch, Jürgen J.; Hegewald, Anne-Kathrin; Breunig, Karin D. Differential control of isocitrate lyase gene transcription by non-fermentable carbon sources in the milk yeast Kluyveromyces lactis *
In: Federation of European Biochemical Societies : FEBS letters . - Amsterdam [u.a.] : Elsevier, Bd. 582.2008, 5, S. 549-557
Publications 2007
Kettner, Karina; Müller, Eva-Christina; Otto, Albrecht; Rödel, Gerhard; Breunig, Karin D. ; Kriegel, Thomas M. Identification and characterization of a novel glucose-phosphorylating enzyme in Kluyveromyces lactis *
In: Federation of European Microbiological Societies : FEMS yeast research . - Oxford [u.a.] : Wiley-Blackwell, Bd. 7.2007, 5, S. 683-692,
Publications 2006
Gbelska, Yvetta; Krijger, Jorrit-Jan; Breunig, Karin D. Evolution of gene families - the multidrug resistance transporter genes in five related yeast species *
In: Federation of European Microbiological Societies : FEMS yeast research . - Oxford [u.a.] : Wiley-Blackwell, Bd. 6.2006, 3, S. 345-355
Anders, Alexander; Lilie, Hauke; Franke, Kathlen; Kapp, Lutz; Stelling, Jörg; Gilles, Ernst D.; Breunig, Karin D. The Galactose Switch in Kluyveromyces lactis Depends on Nuclear Competition between Gal4 and Gal1 for Gal80 Binding *
In: The journal of biological chemistry . - Bethesda, Md. : ASBMB, Bd. 281.2006, 39, S. 29337-29348
Publications 2004
Charbon, Godefroid; Breunig, Karin D. ; Wattiez, Ruddy; Vandenhaute, Jean; Noël-Georis, Isabelle Key Role of Ser562/661 in Snf1-Dependent Regulation of Cat8p in Saccharomyces cerevisiae and Kluyveromyces lactis*
In: Molecular and cellular biology. - Washington, DC : Soc.. - Bd. 24.2004, 10, S. 4083-4091
Publications 2003
Breunig, Karin ; Steensma, H. Yde Kluyveromyces lactis: genetics, physiology, and application *
In: Functional genetics of industrial yeasts. - Berlin [u.a.] : Springer. - 2003, S. 171-206
Wolf, Klaus; Breunig, Karin Non-conventional yeasts in genetics, biochemistry and biotechnology : practical protocols *
Berlin [u.a.] : Springer, 2003. - XXVI, 494 S. : Ill., graph. Darst.. - (Springer lab manual)